About the Workshop
Recent advances in memory research have revealed that memory formation and impairment arise from dynamic interactions across multiple biological scales, ranging from molecular and synaptic processes to distributed neural circuits and brain-wide networks. The EMBO Workshop Cellular and Systems Mechanisms of Memory in Health and Disease is therefore structured to explicitly follow this mechanistic hierarchy. The programme begins with fundamental molecular and cellular processes underlying engram formation and synaptic plasticity, and progressively integrates these insights at the level of synapses, microcircuits, and large-scale networks that support memory encoding and consolidation. Subsequent sessions focus on emerging regulatory mechanisms, including transcriptional, translational, epigenetic, and RNA-based processes, as well as neuromodulatory influences that shape memory persistence and flexibility. These mechanistic frameworks are then extended to understand how memory processes are disrupted in neurodegenerative and neuropsychiatric disorders, highlighting circuit vulnerability and systems-level dysfunction. Throughout the programme, emphasis is placed on novel conceptual advances, cutting-edge methodologies, and unresolved questions, ensuring that the workshop not only consolidates established knowledge but also provides new perspectives on how memory is encoded, maintained, and impaired across levels of brain organization.
A satelite symposium From Synapses to Cognition: Emerging Frontiers in Memory Research will take place on 26 April 2027.
Image credits: Francesca Teo, Siew Cheng Phua lab, National University of Singapore
About EMBO Courses and Workshops
EMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender).
Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.