About the Workshop
Precisely defining transcription unit boundaries across eukaryotic genomes is fundamental to understanding individual gene function and regulation. The multifaceted process of RNA 3' end formation establishes the functional limits of all transcripts, thereby dictating RNA fates. This area has expanded to encompass several 3’ end formation mechanisms, involving new protein complexes, studied across diverse model systems and scientific disciplines using a range of new techniques. Examples of this complexity include different 3' end formation pathways that determine RNA stability or degradation, and the widespread use of alternative 3' end sites used to modulate RNA function and localisation. These diverse outcomes are regulated during development and stress responses, and their dysregulation is implicated in diseases such as infection and cancer. Continued progress necessitates a synthesised understanding of numerous transcriptional processes and the combined expertise of researchers in transcription, RNA processing, localisation and transport, structural biology, bioinformatics, and technology development. Our Oxford 3' end EMBO Workshop brings together scientists with such expertise to discuss RNA 3' ends and their regulation. This will act as a critical catalyst for further progress and provides an important opportunity for early career scientists to share their work and actively engage with this exciting field.
About EMBO Courses and Workshops
EMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender).
Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.
