About the Practical Course
The critical contribution of microbiota to animal, plant and environmental health is now widely accepted. Progress has been driven by two parallel approaches: in silico analyses of large -omics data sets and experimental characterization of host-microbe interactions. Recent advances in computational approaches including metagenomics and multibiome dataset integration are transforming understanding of microbiota composition and dynamics. At the same time, genetically tractable zebrafi sh have emerged as a powerful alternative to rodent models for sophisticated imaging-based characterisation of dynamic host-microbe relationships.
This EMBO Practical Course is designed to give participants a comprehensive exposure to these cutting-edge approaches. You will learn how to sample, sequence, assemble and interpret metagenomes, quantify the host responses they elicit and study the evolution of their constituent taxa and host co-evolution - using a range of genomic, comparative genomic and phylogenetic methods. Concurrently, you will learn how to characterise the impacts of core members of the bacterial microbiome on metabolic signalling in zebrafi sh and determine the eff ects of modifi ed bacterial communities on lipid metabolism using state of the art imaging. This combination of approaches provides a unique opportunity to advance your skills in a field of growing biological and medical relevance.
Image credits: Mckenna Eklund
About EMBO Courses and Workshops
EMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender).
Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.

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