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EMBO Practical Course

In situ structural biology by Cryo-FIB and Cryo-ET

12 – 20 April 2026 | Frankfurt am Main, Germany

  • Registration Deadline
  • 8 Dec 2025
  • Abstract Submission Deadline
  • 8 Dec 2025
  • Chosen Participants Will Be Notified By
  • 22 Dec 2025
  • Payment Deadline
  • 31 Jan 2026

Apply now!

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About the Practical Course

Cryo-focused ion beam/scanning electron microscopy (cryo-FIB/SEM) and cryo-electron tomography (cryo-ET) are emerging, versatile tools for structural cell biologists, aiming at the exploration of molecular landscapes of cells and tissues. Methods and workflows developed to meet this aim are challenging and continuously evolving. This EMBO Practical Course combines focused lectures with intensive hands-on sessions for an in-depth exploration of cryo-FIB/SEM and cryo-ET methods, for participants with prior experience in cryo-electron microscopy. Lectures will provide insights into the principles, methods, and recent achievements of FIB/SEM and electron tomography. Practical modules will allow participants to explore the full cryo-FIB/SEM sample preparation workflow, including sample vitrification and site-specific lamella thinning, advanced procedures such as plasma-focused ion beam milling and correlative cryo-lift-out, as well as tomographic data acquisition and an introduction to current data analysis strategies. The course will include a dedicated day of elective practical sessions to explore advanced methods in data acquisition and processing. These sessions are designed to stimulate curiosity, encourage innovation, and showcase the evolving frontiers of cryo-ET in an interactive and exploratory setting.

This EMBO Practical Course aims at early-career researchers and facility staff members looking to deepen their practical and theoretical understanding of cryo-FIB/SEM and cryo-ET, and to apply and further disseminate these advanced methodologies in structural and cellular biology research.


About EMBO Courses and Workshops

EMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender).

Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.

 
 

Programme

 

Registration

  • Registration Deadline
  • 8 Dec 2025
  • Abstract Submission Deadline
  • 8 Dec 2025
  • Chosen Participants Will Be Notified By
  • 22 Dec 2025
  • Payment Deadline
  • 31 Jan 2026

 

  • STUDENT/POSTDOCS EUR 530
  • ACADEMIC EUR 530
  • INDUSTRY EUR 1600

Registration includes:

  • Accommodation for 8 nights (12 April – 20 April 2026) in standard single rooms. Any additional nights need to be booked and paid personally
  • Coffee breaks
  • Lunches
  • Dinners

Payment

Selected candidates are asked to make payments of the registration fee by 31 January 2026 via bank transfer using the details below.

Reference: pc26/12 Practical Course Firstname Lastname

Banking Information for EUR Bank Transfers:
Deutsche Bank AG
Max-Planck-Gesellschaft zur Förderung der Wissenschaften
BLZ/ sort code: 500 700 10
Account No. 94395100
BIC: Code DEUTDEFFXXX
IBAN: DE08 5007 0010 0094 3951 00

For questions about alternative means of payment, please contact finanzen@biophys.mpg.de

Cancellation Policy

Selected participants are asked to confirm their attendance by email to sonja.welsch@biophys.mpg.de within 14 days of notification (by 5 January 2026).

Participation to the course will be cancelled if the payment has not been made by the 31st of January 2026.

Cancellation of registration by the participant must be submitted via email by 15 February 2026. 100% cancellation fee applies for cancellations made after this date.


Exceptional circumstances: The cancellation policy applies universally but may be adjusted on a case-by-case basis for participants requiring specific arrangements (e.g., visa processing) or due to serious unforeseen circumstances.

Selection criteria

Participants will be selected on the basis of their motivation letter.

In accordance with the guidelines for EMBO Practical Courses, this event is primarily aimed at PhD students and early career researchers. However, as EMBO Practical Courses are promoting the transfer of knowledge and techniques in emerging fields, and considering the specifics of this course, we will also support the attendance of scientific staff members of core facilities and research infrastructures, as well as young research group leaders who have the potential to become multipliers of the acquired knowledge by spreading it to their local scientific communities.

Therefore, we encourage applicants to mention if they have or will have access to cryo-FIB/SEM and cryo-ET instruments after the course.

Application documents

Please submit an abstract, a short CV (max 1 page) and a motivation letter no longer than 2000 characters.

The motivation letter should include your relevant interests and experience, as well as an outline of your research project or your current and future involvement in cryoFIB-/ cryoET projects. Please state why cryo-electron tomography is vital to them, whether you will have access to cryo-FIB and cryo-TEM machines after the course, and how you will be able to spread the knowledge in your local scientific community.

Poster specifications

Selected participants are to bring a printed poster to present their work during the poster session. The poster dimensions should not exceed DIN A0 format.

Travel grants and registration fee waivers

Travel grants and registration fee waivers are available for participants.

Selection of awardees is handled directly by the organizers. EMBO travel grants and registration fee waivers are allocated on the basis of the quality of the submitted abstract.

Applicants do not need to apply separately for these but should indicate on the registration form if they wish to be considered

Additional travel grants are available for EMBC Associate Member States Chile, India, Singapore and Taiwan.

Child care grants

EMBO Courses and Workshops offers grants to offset additional childcare costs incurred by participants or speakers when participating at any EMBO Courses and Workshop funded meeting. Eligible costs include fees for a caregiver or child-care facility, travel costs for a caregiver, or travel costs for taking the child to the meeting etc. Please indicate on the registration form whether you would like to be considered for the grant. Please also describe how you intend to use the childcare grant and specify the sum that you will need.

Accessibility grants

EMBO offers accessibility grants to support participants at EMBO Courses & Workshops with any access needs. These grants cover up to 500 Euros for any additional costs e.g. to adapt the conference environment, or to be accompanied by someone to assist them where necessary.

Participants with access needs may apply for a grant via the registration system of the related EMBO event, or by emailing the organizers of the related EMBO event directly.


Code of conduct

Anti-harassment and non-discrimination policy

At EMBO, we believe that harassment and discriminatory behaviour are unacceptable in any setting.

Media and communications policy

Recording or communication of the presented data needs to be agreed upon by all concerned.

EMBO's code of conduct is applicable for all participants of this EMBO meeting and can be found here.

 

Contact

Sonja Welsch

Email: sonja.welsch@biophys.mpg.de

 

 

Venue

Max Planck Institute of Biophysics

Max-von-Laue-Str. 3
60438 Frankfurt am Main

Germany

Phone (front desk): +49 69 6303-4550

Accommodation

All participants will be accommodated at the same hotel, located approximately a 12-minute walk from the course venue.

A limited number of rooms have also been reserved at the MPI guest house directly adjacent to the venue. These are intended for participants who may require closer accommodation due to mobility considerations, family needs (e.g. attending with a child), or other personal circumstances.

If you would benefit from staying at the guest house, please contact andreas.muench@biophys.mpg.de once your participation is confirmed.

Transport

Plane: Public transport from Frankfurt airport
  • From the airport’s “Regionalbahnhof” Platform 1 take the S-Bahn S8 or S9 (direction Hanau) to Frankfurt city.
  • At Frankfurt Hauptwache transfer to the U8 (direction Riedberg).
  • Exit U8 at Uni Campus Riedberg, turn right to walk to the institute (~5 minutes).

Check the public transport timetable and maps www.rmv.de


Train: Public transport from Frankfurt (Main) Hauptbahnhof

  • Take any S-Bahn S1S9 or U5/U6 from Frankfurt main station’s lower level to Frankfurt Hauptwache.
  • At Hauptwache, transfer to the U8 (direction Riedberg).
  • Exit at Uni Campus Riedberg, turn right to walk to the Institute (~5 minutes).

Car: The Institute ist located at the University Campus Riedberg, in the north of Frankfurt (Main), close to “Bad Homburger Kreuz” of the motorway A5.

  • From “Bad Homburger Kreuz”, take the A661, direction “Offenbach”.
  • Take the second exit “Heddernheim, Riedberg” which merges into “Marie-Curie-Straße”.
  • At the (second) traffic light, take an uphill right turn into “Altenhöfer Allee”.
  • At the first roundabout, turn left into “Max-von-Laue-Straße”.
  • The institute is situated on your left-hand side.

Parking

Available on-campus and a small number of parking lots are available for temporary visitors next to the main entrance to the west of the building. Ask at the porter's lodge how to get access to the institute's main car park (with a barrier) south of the building.

Sustainability at the meeting

The EMBO Courses & Workshops Programme assesses meetings based on the proposal and implementation of sustainability measures. Meetings can earn points across a range of measures, with each measure assigned a point value from one to five. These points classify the meeting into one of three sustainability levels, reflecting the organizers' commitment to enhancing the sustainability of their event. More information on the EMBO Courses & Workshops Sustainability Badge can be found here.

The Max Planck Institute of Biophysics is committed to minimizing the environmental impact of its events. For this reason, the following sustainability measures will be implemented during the workshop:

  • Organizational Support: The event will be organized with support from the Institute’s Sustainability Group, ensuring alignment with our ongoing green initiatives.
  • CO₂ Offsetting: Upon request by invited speakers and tutors, air travel booked through the Max Planck Society travel platform will be CO₂-offset. Additionally, one third of the speakers and tutors are based locally, reducing the need for long-distance travel.
  • Meals: Lunch will be provided through the local university cafeteria, helping to minimize single-use plastics and food transport emissions. Vegetarian and vegan options will be available daily. Dinners will also include vegetarian choices, and milk alternatives will be offered during coffee breaks.
  • Name Tags and Materials: Reusable magnetic name tags will be provided, as used for all our institute events. Paper inserts will be printed for this workshop. Posters, programs, and abstract books will be shared exclusively in digital format to reduce paper waste.
  • Reusable Water Bottles: Each participant will receive a refillable water bottle at the start of the event. Refilling stations will be available throughout the venue. Participants may choose to keep their bottles or return them at the end of the event for cleaning and reuse at future events.
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