About the Workshop
Peroxisomes are central metabolic organelles required for the synthesis of sterols, plasmalogens and certain amino acids, as well as the breakdown of diverse lipids, reactive oxygen species and nucleobases. Peroxisomes have complex pathways of biogenesis and inheritance, multiple ways to import their proteins and they employ diverse ways to transport metabolites. Since peroxisomes share many functions and proteins, such as their fission machinery, with mitochondria, the interplay between these two major metabolic hubs is intriguing. Peroxisomes also exhibit diversity in size, number, and protein content, all of which can be altered in response to metabolic and environmental signals. Peroxisomes are essential for activating innate immune signaling to promote survival in the face of microbial challenges. Importantly, impaired function of peroxisomes gives rise to severe peroxisomal diseases. Beyond such inborn errors, peroxisomes contribute to different aspects of human health and disease such as aging as well as multiple and prevalent diseases including cancer, viral infection, diabetes, and neurodegeneration. Despite the clear importance of peroxisomes in common pathophysiological processes, research on the mechanisms underlying their contributions is still sparse. This meeting is the first EMBO meeting on peroxisomes and will shine a light on peroxisomes in current research on central, abundant, and society-impacting human pathologies.
About EMBO Courses and Workshops
EMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender).
Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.
