About the India-EMBO Lecture Course
Approximately 7000 human proteins are compartmentalized within a subcellular organelle at one point of their cellular life. A majority of these proteins are obligate organelle residents. With the exception of 13 mitochondrial proteins, organelle proteins are synthesized in the cytoplasm and imported afterwards. The 13 mitochondria-encoded proteins interact with other imported proteins in impeccable stoichiometry to constitute functional protein complexes. Thus, a synchrony in biogenesis, cytosolic quality control, import, and quality control of the imported proteins within the organelles is imperative to maintain the homeostasis of organelle-proteomes. Further, recent advances in cell biology tools revealed multiple organelle contact sites populated with specific proteins that play fundamental roles in cross-organelle transport of proteins and lipids. Many non-resident proteins are now known to spatiotemporally localize to cell organelles for quality control. The EMBO India lecture course aims at introducing the latest conceptual frameworks and methodological advances related to the molecular assembly, function, and regulatory frameworks of biogenesis and quality control of organelle proteins in physiology and in pathological contexts. We will provide the students a multidisciplinary technical background through the organization of methodological workshops, and promote interactions through meet-the-speaker and informal round table discussions. Applications from researchers/scientists from all levels will be encouraged.
About EMBO Courses and Workshops
EMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender).
Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.
