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EMBO Practical Course

iCLIP2, mapping protein-RNA interactions: from A to Z

07 – 12 September 2025 | Genoa, Italy

  • Registration
  • 5 March–31 May 2025
  • Abstract Submission Deadline
  • 31 May 2025
  • Chosen Participants Will Be Notified By
  • 10 June 2025
  • Payment Deadline
  • 30 June 2025

Apply now!

Use #EMBOiCLIP2

Download calendar invitation

About the Practical Course

RNA is increasingly recognized as a key therapeutic target, driving the development of RNA-based therapeutics for a broad spectrum of diseases. RNA-binding proteins (RBPs) play a fundamental role in regulating RNA function, and identifying their targets and molecular interactions is essential for understanding their cellular roles.

The advent of high-throughput RNA interaction mapping techniques, such as UV crosslinking and immunoprecipitation (CLIP) coupled with next-generation sequencing, has revolutionized our understanding of RNA regulation. In recent years, advanced CLIP methodologies have been developed that enhance efficiency, speed, and analytical depth, providing a more comprehensive view of protein-RNA interactions.

This course offers hands-on training in the iCLIP2 protocol, a cutting-edge high-resolution CLIP technique for transcriptome-wide RNA-interaction mapping. The key objectives are to:
(i) Guide participants through the complete iCLIP2 workflow, from experimental setup to data generation.
(ii) Introduce and apply bioinformatics approaches for CLIP data analysis, equipping participants with essential computational skills.
(iii) Explore alternative and specialized CLIP protocols, including seCLIP, kinCLIP, and miCLIP2, discussing their unique advantages and applications.

Theoretical sessions will cover the principles and advancements of iCLIP2 and related CLIP protocols, while practical bioinformatics modules will provide essential tools for analyzing large-scale interaction datasets. This course is designed for PhD students, postdoctoral researchers, and scientists working in RNA biology, transcriptomics, and RNA-based therapeutics, offering valuable insights into cutting-edge methodologies in RNA regulation research.

Image credits: Heng-Chang Chen


About EMBO Courses and Workshops

EMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender).

Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.

 

Speakers

 

Programme

 

Registration

  • Registration
  • 5 March–31 May 2025
  • Abstract Submission Deadline
  • 31 May 2025
  • Chosen Participants Will Be Notified By
  • 10 June 2025
  • Payment Deadline
  • 30 June 2025

 

  • STUDENT/POSTDOCS EUR 550
  • ACADEMIC EUR 750
  • INDUSTRY EUR 1000

Registration includes:

  • Registration includes:

  • All course material
  • Accommodation in shared double rooms.
  • Lunches, coffee breaks and social activities
  • Transport back and forth from the hotel to IIT
  • Welcome dinner
  • Cheese and wine evening and one additional dinner
  • Farewell drinks & snacks

Payment

Payment will be done through an external link that will be sent to the selected participants.

Cancellation Policy

Participants may cancel their attendance up to 45 days before the course start date for a full refund. Cancellations made after this period will only be eligible for reimbursement if the vacant spot can be successfully filled.

Selection criteria

Participants will be selected based on their:

  • Their background in Protein-RNA interactions (CV)
  • Research experience in the RNA field (Abstract)
  • Motivation and genuine interest in the course how it relates to their research or career goals
  • Diversity and inclusivity, gender balance, geographic representation researchers from underrepresented regions or backgrounds.

Note that we can select more than 10% of the participants from the same country.

Abstract guidelines

Abstract should be less than 250 words, including a brief summary of the research topic and the main findings.

Poster specifications

Length: 110 cm

Width: 80 cm

Additional Requirements

  • CV

  • Motivation letter

Travel grants and registration fee waivers

Travel grants and registration fee waivers are available for participants. Selection of awardees is handled directly by the organizers. EMBO travel grants and registration fee waivers are allocated on the basis of the quality of the submitted abstract.

Applicants do not need to apply separately for these but should indicate on the registration form if they wish to be considered.

Additional travel grants are available for EMBC Associate Member States Chile, India, Singapore and Taiwan.

Child care grants

EMBO Courses and Workshops offers grants to offset additional childcare costs incurred by participants or speakers when participating at any EMBO Courses and Workshop funded meeting. Eligible costs include fees for a caregiver or child-care facility, travel costs for a caregiver, or travel costs for taking the child to the meeting etc. Please indicate on the registration form whether you would like to be considered for the grant. Please also describe how you intend to use the childcare grant and specify the sum that you will need.

Code of conduct

Anti-harassment and non-discrimination policy

At EMBO, we believe that harassment and discriminatory behaviour are unacceptable in any setting.

Media and communications policy

Recording or communication of the presented data needs to be agreed upon by all concerned.

EMBO's code of conduct is applicable for all participants of this EMBO meeting and can be found here.

 

Contact

Eva Ferri

Email: Eva.ferri@iit.it

 

 

Venue

Istituto Italiano di Tecnologia (IIT)

Center for Human Technologies

Via Enrico Melen 83, Building B

16152 Genova, Italy

Accommodation

Students will be accommodated at Best Western City hotel, they will have shared rooms.

Transport

Genova can be reached by plane (Genova, Columbus Airport), by train, two main stations (Genova Piazza Principe, Genova Brignole) and by bus (Flixbus, Genova Piazza Fanti)

About the Area

Genova is one of the biggest cities of Liguria region, in the north west of Italy. It is a Mediterranean city hosting the biggest aquarium in Italy, several museums and historical parts that are listed as UNESCO World Heritage. Genova is very close to the famous Cinque Terre villages, they can be easily reached by train and a hike between the villages is highly recommended to appreciate the beauty of the Mediterranean coast. It is also close to Santa Margarita and Portofino.

Sustainability at the meeting

The EMBO Courses & Workshops Programme assesses meetings based on the proposal and implementation of sustainability measures. Meetings can earn points across a range of measures, with each measure assigned a point value from one to five. These points classify the meeting into one of three sustainability levels, reflecting the organizers' commitment to enhancing the sustainability of their event. More information on the EMBO Courses & Workshops Sustainability Badge can be found here.

During the course, we will follow the IIT standards for CO2 footprint. we will apply a combination of measures including:

  • Sustainable accommodations: we chose eco-friendly and sustainable hotels with green certification, that use eco-friendly toiletries, and are equipped with a system to turn off lights and electronics when not in use, and adjust the temperature to save energy
  • Sustainable transportation: If we must rent a shuttle bus, we will choose the most fuel-efficient option available.
  • Reduce food waste: The dinners will be held at restaurants that prioritize sustainability and reduce food waste. During the course we will avoid single-use plastics and plastic water bottle and cutlery. We will have at least one vegetarian meal
  • Reduce energy consumption: We will turn off lights, machines, electronics, air conditioning when not in use.
Molecular Systems Biology