About the Workshop
Resident immune cells are present in all organs of the body. They span both myeloid and lymphoid cell lineages and include macrophages, mast cells, innate lymphoid cells, memory T and B cells and non-classical T cells. These cells are adapted to meet local requirements, but also share core properties across sites. Besides their roles as immune sentinels, tissue-resident immune cells also detect perturbations in homeostasis and contribute to developmental processes, normal organ functioning and pathology. They are thus essential for homeostasis, health and disease.
Recent advancements in genetic fate-mapping and single-cell profiling have shed further light on biology of these cells. However, there are still gaps in our knowledge. For example, we have yet to understand the full extent of unique and shared features between sites and lineages. Similarly, the mechanisms responsible for the positioning and retention of immune cells within their niches remain poorly understood.
This workshop will provide an up-to-date overview of recent discoveries concerning the ontogeny, functions and positioning of tissue-resident immune cells. It brings together leading experts of all career stages, who cover a wide range of lineages, organs and biological contexts, making this a unique opportunity for those interested in tissue immunity beyond individual aspects.
Participants will therefore have the unique opportunity to explore shared and specific aspects of resident immune cell biology, which is not possible at meetings focused on individual lineages, tissues or conditions. This will inform future strategies for targeted modulation of resident immune cells in the treatment of cancers, infections, and autoimmune or inflammatory diseases.
Satellite Meeting: Luminy Advanced Course in Immunology, March 18 to 20, 2024.
On the preceding days, a 3-day training course is offered at Center of Immunology at Marseille Luminy (CIML) for 24 PhD students or Early Stage Researchers interested by the topic of the EMBO workshop and willing to acquire skills in cutting edge immunological techniques. Taught by leading experts in the field of Spectral Flow Cytometry, Light sheet /3D microscopy and Spatial Transcriptomics, the course will provide expert tuition in workflows and analysis pipelines with access to state-of-the-art equipment and software in a small group format.
About EMBO Courses and Workshops
EMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender).
Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.
