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EMBO Workshop

The ISG15 system in molecular function and disease mechanisms

01 – 04 June 2022 | Berlin, Germany

EMBO Childcare Grants Logo

  • Registration Deadline
  • 25 April 2022
  • Abstract Submission Deadline
  • 25 April 2022
  • Chosen Participants Will Be Notified By
  • 1 week after submission deadline
  • Payment Deadline
  • 20 May 2022

Apply now!

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About the Workshop

Interferon-stimulated gene 15 (ISG15) was the first ubiquitin-like protein to be discovered. As it is robustly induced by pathogen infection, its initial characterization was limited to innate immunity. It is now clear that the ISG15 system, including the conjugation machinery and the deconjugase USP18, plays key roles in other biological contexts. Patients with inborn errors in ISG15 and USP18 exhibit severe pathologies highlighting the important role of the ISG15 system in health and disease. Recent breakthroughs have revealed the physiological relevance of ISG15 in its dual roles as a cytokine and conjugation system in both mouse models and human patients, however the diversity of biological processes regulated by ISG15/USP18 as well as the mechanistic insights of its activity remain enigmatic.

ISG15 research gained a lot of attention by the coronavirus pandemic. Like other viruses SARS-Cov-2 developed ISG15 evasion mechanisms that are pursued as drug target, an actual atopic that will be covered during the workshop.

This is the first meeting bringing together scientists working on ISG15, ISGylation and USP18 to foster interdisciplinary interaction and collaboration. Topics will cover the role of ISG15 system in immunity, pathogen response, cancer, genome stability and metabolism. New tools and strategies to investigate molecular mechanisms of ISG15 will be presented. The meeting will discuss the clinical implications for patients with malfunctions and mutations in ISG15, USP18 or associated molecules.

Thereby, this EMBO Workshop will provide a unique platform to create a novel scientific community with various focus and background tied together by a common interest in the ISG15 system.

 

Speakers

 

Programme

 

Registration

  • Registration Deadline
  • 25 April 2022
  • Abstract Submission Deadline
  • 25 April 2022
  • Chosen Participants Will Be Notified By
  • 1 week after submission deadline
  • Payment Deadline
  • 20 May 2022

 

  • STUDENT/POSTDOCS EUR 400
  • ACADEMIC EUR 450
  • INDUSTRY EUR 700

Registration includes:

  • Conference material
  • Coffee breaks and refreshments at poster sessions
  • Lunch and dinner
  • Festive dinner (Königliche Gartenakademie)
  • Berlin-Dahlem Campus tour – guided tour (optional)

Registration fee does NOT include accommodation

Payment

Payment information will be provided shortly.

Selection criteria

All applicants are encouraged to present their work as a talk or poster. Ten talks will be selected from abstracts, and 20 posters of high interest will be highlighted by 'flash talk' sessions. Applicants should indicate their preference at abstract submission.

Selection criteria:

  • Scientific quality of the abstract
  • Relevance to the theme of the workshop
  • Priority will be given to early stage researcher
  • Balance of participants from different countries, genders, and career stages

For participants who do not plan to present their work, a CV is kindly requested and will be used to decide about admission.

Abstract guidelines

Abstract maximum length is 200 words, not including title, author names and affiliations. Abstracts must be written in English and should clearly indicate scientific relevance, results and conclusions.

Poster specifications

Please bring one printed copy of your poster in portrait orientation (NOT landscape). Dimensions of the poster boards are 100 cm wide by 135 cm high.

Push pins or Velcro for hanging the posters will be provided.

Travel grants

A limited number of travel grants are available for participants. Applicants do not need to apply separately for travel grants for this event but should indicate on the registration form if they wish to be considered for a travel grant. Selection of awardees is handled directly by the organizer who will notify all eligible participants. More information is available at EMBO Travel Grants' page.

Specific travel grants and fee waivers are available for participants of any nationality working in laboratories in Chile, India, Singapore and Taiwan. To apply, please send an email directly to the meeting organisers justifying your request.

Child care grant

EMBO Courses and Workshops offers grants to offset additional child care costs incurred by participants or speakers when participating at any EMBO Courses and Workshop funded meeting. Eligible costs include fees for a caregiver or child-care facility, travel costs for a caregiver, or travel costs for taking the child to the meeting etc. Please indicate on the registration form whether you would like to be considered for the grant. Please also describe how you intend to use the child care grant and specify the sum that you will need.

 

Contact

Klaus-Peter Knobeloch

Email: klaus-peter.knobeloch@uniklinik-freiburg.de

 

 

Venue

Harnack House
The Conference Venue of the Max Planck Society
Ihnestr. 16-20 14195 Berlin
Phone: +49 30 8413-3800
Fax: +49 30 8413-3801
Email: info@harnackhaus-berlin.mpg.de

Click here for the booking link for participants.

Accommodation

Accommodation (single-room) is available on-site to the conference venue at the Harnack-House for a limited number of participants. A list of hotels can be found here. We recommend to book as soon as possible!

Transport

Start at airport Tegel (18 km)

...take Bus 109 towards Zoologischer Garten and alight at Jakob-Kaiser-Platz. Then enter the U-Bahn and take the U7 towards Rudow. At Fehrbelliner Platz, change onto the U3 towards Krumme Lanke and alight at Freie Universität (Thielplatz). To exit the station, follow the train’s direction of travel and take the left exit. From there, bear right; you will reach Harnack House after approximately 100 meters.

Start at airport Berlin Schoenefeld (25 km)

...take Bus 171 to Rudow U-Bahn station. Enter the U-Bahn and take the U7 towards Rathaus Spandau. At Fehrbelliner Platz, change onto the U3 towards Krumme Lanke and alight at Freie Universität (Thielplatz). To exit the station, follow the train’s direction of travel and take the left exit. From there, bear right; you will reach Harnack House after approximately 100 meters.

Start at Berlin´s Central Station Hauptbahnhof (15 km)

...take S-Bahn line S7 towards Potsdam Hauptbahnhof. At Zoologischer Garten, change onto the U9 towards Rathaus Steglitz. At Spichernstrasse, change onto the U3 towards Krumme Lanke and alight at Freie Universität (Thielplatz). To exit the station, follow the train’s direction of travel and take the left exit. From there, bear right; you will reach Harnack House after approximately 100 meters.

Start at train station Südkreuz (9 km)

...take the S41 (Ringbahn) and alight at Heidelberger Platz. Change onto the U3 towards Krumme Lanke and alight at Freie Universität (Thielplatz). To exit the station, follow the train’s direction of travel and take the left exit. From there, bear right; you will reach Harnack House after approximately 100 meters.

From Spandau train station (17 km)

...take U-Bahn line U7 towards Rudow and alight at Fehrbelliner Platz. Change onto the U3 towards Krumme Lanke and alight at Freie Universität (Thielplatz). To exit the station, follow the train’s direction of travel and take the left exit. From there, bear right; you will reach Harnack House after approximately 100 meters.

Arrival by car

...when approaching on the A 115, take Hüttenweg No. 2 exit. Then bear right towards Dahlem and continue until you reach the junction with Clayallee. Turn right. At the next junction, turn left into Saargemünder Strasse. Harnack House is on the right shortly after at the corner of Ihnestrasse.

COVID-19 Regulations

1) Travel to Germany

There are currently no pandemic-related restrictions on entry from the member states of the European Union, Switzerland, Liechtenstein, Norway and Iceland.

For all other countries, there will be a general obligation for persons aged twelve and over to carry a COVID certificate when entering Germany. Persons aged twelve years and older must have proof of testing or proof of convalescence or proof of vaccination when entering Germany. In principle, COVID tests (antigen tests or PCR tests) may not be older than 48h at the (planned) time of entry. In the case of entry with a carrier (e.g. airline), PCR tests may not be older than 48 hours at the (planned) time of the start of the journey (e.g. departure time); antigen tests may not be older than 48 hours at the (planned) time of entry, even when travelling with a carrier.

Detailed information can be found here.

2) Venue

The Harnack House is guided by the requirements of the Federal Infection Protection Act, according to which distance rules will no longer have to be observed. There will no longer be any access restrictions. A voluntary test is nevertheless recommended.
A free test station is located at the entrance to lecture hall l (open Mon - Fri 7:30 a.m. to 4:30 p.m.).

Likewise, the obligation to wear a mask is no longer applicable, but we ask our participants to wear a mask in the lecture rooms. As far as possible, we will use the outdoor areas for breaks and individual parts of the event.

EMBO Molecular Medicine