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EMBO Workshop

DNA Topology in genomic transactions

20 – 23 September 2021 | Virtual

  • Virtual event icon
    Virtual event
  • Registration Deadline
  • 30 August 2021
  • Abstract Submission Deadline
  • 30 July 2021
  • Chosen Participants Will Be Notified By
  • 20 August 2021
  • Payment Deadline
  • 10 September 2021

Apply now!

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About the Workshop

The helical structure of DNA and the compaction of our two-meter-long genome into a confined nuclear volume creates a variety of DNA topological challenges to the cell. Cellular processes, such as replication and transcription, induce dramatic changes in DNA topology, including DNA supercoiling, knots, and entanglements. These changes occur in the context of chromatin and therefore must be coordinated with other chromatin processes, such as chromosome segregation, higher-order chromosome folding and repair. The action of specialised enzymes, such as DNA topoisomerases, solve topological problems and coordinate these processes in space and time. Defects in controlling DNA topology lead to genomic instability and are associated with cancer and neurodegeneration. An integrated understanding of genome metabolism must therefore consider how dedicated factors shape the topological context of DNA processes, and how this is regulated to maintain faithful transmission of genetic information to the daughter cells.

This Workshop will cover emerging fundamental aspects of factors governing DNA topology and its impact on critical cellular processes of genome metabolism, including transcription, replication, segregation, chromosome architecture and repair. We aim to provide a global view of how controlling DNA topology acts as a keystone of genome dynamics.

The EMBO Workshop will be streamed live from the AppInConf platform. To access, please use this link:

Image credit: Valerie Lamour, Vassilis Roukos, Joaquin Roca

About EMBO Courses and Workshops

EMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender).

Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.







  • Registration Deadline
  • 30 August 2021
  • Abstract Submission Deadline
  • 30 July 2021
  • Chosen Participants Will Be Notified By
  • 20 August 2021
  • Payment Deadline
  • 10 September 2021



Registration includes:

  • The registration fee includes access to the online platform.


Payment will be connected to 3D Secure system and can be performed via credit card, invoice or bank transfer.

Selection criteria

Participants will be selected on scientific grounds, gender balance and geographical distribution (broad distribution).

Abstract guidelines

Abstracts must be a maximum of 250 words, excluding the title, authors and affiliations.

Poster specifications

Poster presenters could prepare pre-recorded flash-talk of maximum 3 minutes and/or a PDF file of their poster. Poster presenters will be able to discuss with other participants during the poster session.

Travel grants

In lieu of travel grants, a number of fee waivers will be available for participants. Applicants do not need to apply separately for fee waivers for this event but should indicate on the registration form if they wish to be considered for a fee waiver. Selection of awardees is handled directly by the organizer who will notify all eligible participants. More information is available at EMBO Travel Grants' page.

Specific fee waivers are available for participants of any nationality working in laboratories in Chile, India, Singapore and Taiwan. To apply, please send an email directly to the meeting organisers justifying your request.

Child care grant

EMBO Courses and Workshops offers grants to offset additional child care costs incurred by participants or speakers when participating at any EMBO Courses and Workshop funded meeting. Eligible costs include fees for a caregiver or child-care facility, travel costs for a caregiver, or travel costs for taking the child to the meeting etc. Please indicate on the registration form whether you would like to be considered for the grant. Please also describe how you intend to use the child care grant and specify the sum that you will need.

Additional Information

Please note that we will record all the talks and save the questions from the audience to be available to registered participants on the EMBO platform during the workshop and for 10 days after completion of the workshop. If you do not agree to share your presentation and questions, please let us know by email (




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