About the India-EMBO Symposium
Despite the DOTS multi-drug treatment regimen in clinical practice for more than two decades, TB continues to be a leading cause of mortality due to infectious diseases. Interestingly, emergent problems of increased incidence of MDR/XDR strains along with the dramatic increase in EPTB cases is creating a challenging scenario for India’s ambition of eliminating TB by 2025. While remarkable scientific insights have been decoded in these last two decades with regard to TB pathogenesis; TB diagnosis and treatment regimens have completely remained insulated from these developments. A feature that has lagged behind in terms of treatment modalities is the role of the host cells and tissues in modulating disease trajectories. In fact, it is now clear that host-pathogen crosstalk is the key determinant influencing the outcome of Mtb infection. Another hidden danger with long-term treatment is of creating an AMR reservoir in the intestinal microbiome of these patients. Increasingly, several studies highlight the links between the microbiota and the immune system of the host. This meeting is an attempt to deliberate o n these new paradigms and bring some of these aspects into the mainstream practice providing impetus towards accelerated clinical outcomes. T
The thematic areas of the meeting will be:
- Clinical Workshop
- Phenotypic heterogeneity and persistence
- Mycobacterial lifestyle and metabolism in the host microenvironment
- Alternate niches of mycobacteria
- Host microenvironment and signaling
- Systems biology of mycobacterial pathogenesis
- Drug resistance in tuberculosis
- Mycobacteria and host immunity
- Extra-pulmonary tuberculosis
About EMBO Courses and Workshops
EMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender).
Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.