About the Practical Course
Problems in structural biology today can very often not be solved by one technique alone, but require a combination of methods, including NMR, X-ray crystallography, electron microscopy, structural mass spectrometry, and SAXS. The heterogeneous data obtained by these methods need to be combined with advanced molecular modeling techniques. The goal of the course is to provide young scientists that have more specialized knowledge in one of the techniques an overview over the broad range of modern structural methods available. The course includes practical training in computational approaches to integrate data (such as IMP, HADDOCK, ...). The course is principally aimed at the mature graduate student / postdoctoral level, but applications from scientists at all levels will be encouraged. The course will consist of lectures, which will give introductions into the principles and limitations of the different techniques, and practical work on data analysis with the major structure refinement / modeling programs.