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EMBO Practical Course

High-throughput protein production and crystallization

10 – 19 June 2019 | Didcot, United Kingdom

  • Registration Deadline
  • 12 April 2019
  • Chosen Participants Will Be Notified By
  • 30 April 2019
  • Payment Deadline
  • 31 May 2019

Apply now!

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About the Practical Course

Production of recombinant proteins using bacterial and eukaryotic hosts is the basis of research into biological structure and function. Advances in technology and throughput in the areas of protein production and structural biology have enabled many more challenging proteins to be studied to help in understanding their function. For instance, the recent advancement of cryo-electron microscopy has made the technique suitable for a broader range of proteins whose structure could previously only be determined by X-ray crystallography. This has been particularly transformative for the challenging field of membrane protein structural biology. At this EMBO Practical Course, participants will learn our well-established high-throughput approaches for expression screening and purifying proteins for crystallization. Additionally, they will gain hands-on experience in technologies to reconstitute integral membrane proteins into detergent-free systems, such as nanodiscs, Salipro, amphipols and SMALPs, because these have been key to achieve high resolution structures by cryo-EM.

About EMBO Courses and Workshops

EMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender).

Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.







  • Registration Deadline
  • 12 April 2019
  • Chosen Participants Will Be Notified By
  • 30 April 2019
  • Payment Deadline
  • 31 May 2019



Registration includes:

  • Accommodation
  • Meals
  • Course materials


Participants will be sent details by the Admin team in the form of an email explaining how payment can be made.

Selection criteria

The participants of the course will be mainly PhD students and early career scientists and post-docs. One or two experienced staff acting as core facility manager may be selected.

The main criteria will be the motivation of the participants to introduce high-throughput methods successfully in their current research activities, i.e. working on a large number of proteins or variants or working on challenging proteins such as membrane proteins or protein complexes.

Priority will be given to applicants whose projects are most relevant to the objectives of the course to maximize the benefit for both themselves and their research groups.

For applications to be successful, applicants must complete the application page as well as submit a short CV, a motivation letter and a letter of support from their supervisor or another senior co-worker.

Poster specifications

Dimensions of poster boards are: 100 (width) x 150 (length) cm

Travel grants

A limited number of travel grants are available for participants. Applicants do not need to apply separately for travel grants for this event but should indicate on the registration form if they wish to be considered for a travel grant. Selection of awardees is handled directly by the organizer who will notify all eligible participants. More information is available at EMBO Travel Grants' page.

Child care grant

EMBO Courses and Workshops offers grants to offset additional child care costs incurred by participants or speakers when participating at any EMBO Courses and Workshop funded meeting. Eligible costs include fees for a caregiver or child-care facility, travel costs for a caregiver, or travel costs for taking the child to the meeting etc. Please indicate on the registration form whether you would like to be considered for the grant. Please also describe how you intend to use the child care grant and specify the sum that you will need.



Admin Team Contact:

Natsumi Astley


Nicola Burgess-Brown




Research Complex at Harwell

R92 Rutherford Appleton Laboratory

Harwell Oxford




The Cosener's House

15-16 Abbey Cl,

Abingdon OX14 3JD

There will be a daily coach transfer from Abingdon to the Rutherford Appleton Laboratory campus.


The Research Complex at Harwell is located on the Rutherford Appleton Laboratory campus which has ‘bus/rail links (railway station at Didcot 6 miles away) to Oxford and Reading where there are frequent direct ‘bus connections to Heathrow and Gatwick airports. For further details see here.

About the Area

The venue for the course is the Research Complex at Harwell located on the Rutherford Appleton Laboratory campus which is 15 miles south of Oxford in the heart of the Oxfordshire countryside.

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