About the Global Exchange Lecture Course
Structural methods applicable to solutions facilitate structural and functional studies on biological macromolecules under close to native conditions. Fully exploiting this opportunity allows one to extract the maximum amount of biologically meaningful information and to relate the structural results to the function of the system. The main objective of this EMBO course is to train graduate students and postdocs in state-of-the-art methods to study biological macromolecules in solution. We aim at a comprehensive coverage of the major structural and biophysical techniques employed for characterization of high and low resolution structure and structural transitions, macromolecular complex formation, protein folding, stability, interactions and enzymatic mechanisms.
The EMBO course will include lectures on:
- Small-angle X-ray and neutron scattering (SAXS/SANS)
- Nuclear magnetic resonance (NMR)
- Light scattering, hydrodynamic, calorimetric and spectroscopic approaches.
- Cryo-electron microscopy (cryoEM)
- Bioinformatic tools to analyse protein-protein interactions
- Macromolecular crystallography (MX)
Special attention will be paid to interdisciplinary approaches, where the synergistic use of complementary techniques leads to a comprehensive description of macromolecular systems.
About EMBO Courses and Workshops
EMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender).
Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.