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EMBO Practical Course

iCLIP: Genomic views of protein-RNA interactions

26 March – 01 April 2017 | Mainz, Germany

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  • Registration Deadline
  • 15 January 2017
  • Chosen Participants Will Be Notified By
  • 01 February 2017
  • Payment Deadline
  • 01 March 2017

Apply now!


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About the Practical Course

Practical Course illustration

Throughout its life cycle, each RNA will interact dynamically with numerous RNA-binding proteins (RBPs) that determine how the RNA is processed, where it is localized, whether it is translated and finally how it is degraded. In turn, RBPs can interact with hundreds to thousands of cellular RNAs by recognizing certain sequence motifs or structural elements. Understanding these interactions in a genome-wide manner is crucial for gaining a complete picture of an RBP’s specificity and function.

Individual-nucleotide resolution UV crosslinking and immunoprecipitation (iCLIP) has established itself as a leading method to map the RNA interaction sites of a single RBP-of-interest with high resolution and in a quantitative manner. The major objective of this EMBO Practical Course is to disseminate the knowledge and proficiency in this technically challenging ribonomics method. We will guide the participants through the complete protocol, placing special emphasis on critical optimisation steps and controls. We will further discuss the bioinformatics strategies for analysis of iCLIP data. The hands-on sessions in the laboratory will be complemented by presentations by established scientists that will share their experience on using iCLIP to answer different biological questions.







  • Registration Deadline
  • 15 January 2017
  • Chosen Participants Will Be Notified By
  • 01 February 2017
  • Payment Deadline
  • 01 March 2017



Registration includes:

  • course fees
  • course materials
  • accommodation in single rooms
  • full catering (breakfast, lunch, dinner, refreshments)


Payment details will be sent to successful applicants.

Selection criteria

The course is limited to 18 participants, which will be selected according to the following criteria:

  • Participants should have experience in experimental RNA biology.
  • The course content should be relevant to their research, i.e. participants should be likely to use e.g. iCLIP or related technologies (Hits-CLIP, PAR-CLIP, ribosome profiling) as part of their project in the near future.
  • We will prioritise applications from junior researchers at the PhD and early postdoc stage.

Applicants are required to provide the following information:

  • Statement of motivation (max. 2000 characters including spaces)
    • include your relevant skills, experience and qualifications which show that you would be suitable for the practical course.
    • explain why you would like to attend, including what you can contribute and how you think you will benefit from the practical course.
  • Abstract of your current research (max. 1500 characters including spaces)
  • Concise CV

Only complete applications will be considered. Applications will be evaluated and selected by the organisers based on suitability for the course. Selected participants will be contacted by e-mail by February 1st, 2017. If positions remain open future rounds of selection will be performed, therefore you might be notified later.

For participants that already started with their own iCLIP experiments at home, it will be possible to bring their own samples under certain conditions. If you are interested in this option, please contact for more details.

Poster Specifications

The maximum size should be 120 cm width/150 cm height.

Travel Grants

A limited number of travel grants are available for participants. Applicants do not need to apply separately for travel grants for this event but should indicate on the registration form whether they wish to be considered for a travel grant. Selection of awardees is handled directly by the organizer who will notify all eligible participants. More information is available at EMBO Travel Grants.






Institute of Molecular Biology (IMB)

Ackermannweg 4

55128 Mainz


Participants, instructors and speakers will stay in single rooms at the Advena Europa Hotel, located within walking distance from the main train station (2 minutes) and the city centre (15 minutes). All guest rooms have free WiFi access.

Advena Europe Hotel

Kaiserstr. 7

55116 Mainz


Arriving by plane

There are two airports near Mainz:

Frankfurt International Airport
• train (EC, ICE, IC, RE, RB) or S-Bahn (line S8) transit from Frankfurt International Airport to Mainz main station
• duration: 30-40 minutes
• ticket price: €4-8 (depending on the train)
• for schedule information see:

Airport Frankfurt-Hahn (Hunsrück)
• bus transfer to Mainz main station: ORN from terminal 3 (leaves Frankfurt-Hahn every 3 hours)
• duration: 90 minutes
• ticket price: approx. €10
• for schedule information click here.

Arriving by train

The best way to reach IMB from the train station is the bus line #69 (‘Campuslinie’) via the Mainz University Campus. The bus stop Duesbergweg is located in front of the IMB building. For more information click here.

About the Area

The city of Mainz is a charming, open-minded city. It dates back 2,000 years to Roman times and still has a historic centre with a magnificent medieval cathedral. It was also here, in 1450, that Johannes Gutenberg invented modern book printing. The city is located at the confluence of two of the most important rivers in Germany, the Rhine and the Main, and has spectacular esplanades.

Mainz is within easy reach of both cosmopolitan Frankfurt, with its famous opera house, avant-garde museums and glass-and-steel banking district, and the Rhine valley region with its castles, vineyards and nature reserves that offer great outdoor activities.

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