About the Practical Course
In collaboration with EMBO we are looking forward to host yet another practical course in Odense, Denmark. Attending this EMBO Practical Course will provide you with hands-on experience within the field of protein post-translational modifications (PTMs) and you will obtain a new and solid network of scientists having interests similar to yours. Our bright new laboratory and large mass spectrometry instrument park will provide the physical framework for the 8-day course.
Modifications of proteins is an essential mechanism used by cells to achieve a tight and controlled regulation of cellular mechanisms and perturbations in PTM regulation often leads to serious diseases. Increasing evidence suggest that PTMs are frequently not working alone but can have significant influence on the presence and function of other PTMs in a way that a given PTM of a given protein can affect other PTMs either on the same or other proteins, leading to distinct functional patterns of PTMs on proteins, tightly regulating important functions in the cell, a phenomenon termed PTM cross-talking.
This EMBO Practical Course aims to provide a theoretical and practical overview of state-of-art techniques for the characterization of various PTMs, such as phosphorylation, acetylation, cysteine PTMs and glycosylation, and their cross-talking in controlling dynamic cellular mechanisms.
The laboratory part will focus on a case study of EGF stimulated SILAC labeled HeLa cells. You will be introduced to enrichment, identification and quantitation of the PTM peptides and to mass spectrometry analysis as well as data interpretation and bioinformatics. This will provide you with knowledge needed to perform quantitative large scale PTMomics from small amount of sample material yourself. You will be taught in methods developed in the laboratories of the speakers and they will provide you with their own tips and tricks.
In addition to lectures and laboratory work the program contains poster sessions, group discussions, learning activities, and social events. All students will be accommodated together in a nice hotel in the center of the birth city of H.C. Andersen.
Below you find some comments from participants last year:
“The meeting encompassed many inspiring talks, which enabled me to gain some new perspectives and ideas about my work.“
“The most current advances in methods to study PTMs were covered well. Also, many speakers shared recent research from their own lab“
“It was great to discuss the ideas of my study through the poster session with the scientists and participants from different research backgrounds. I got some important suggestions which I could implement in my study.”
“The organization of the course was excellent during the course.” “The most current advances in methods to study PTMs were covered well. Also, many speakers shared recent research from their own lab“
“I think the meeting was just excellent! I got the best from it and I will honestly recommend it to my colleagues. We learned a lot, we had excellent speakers and I met great people with whom hopefully I am planning meetings in future!”