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EMBO Childcare Grants Logo

EMBO Practical Course

Mouse genome engineering

25 August – 06 September 2019 | Dresden, Germany

EMBO Childcare Grants Logo
  • Registration Deadline
  • 30 April 2019
  • Abstract Submission Deadline
  • 30 April 2019
  • Chosen Participants Will Be Notified By
  • 13 May 2019
  • Payment Deadline
  • 10 June 2019

Apply now!

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About the Practical Course

The mouse remains the main vertebrate model for a wide range of biological problems. The field of mouse genetics was completely reshaped with the advent of new methods for genome engineering harnessing RNA-guided nucleases of the bacterial CRISPR/Cas system. Principally new methods and dramatic improvements in existing techniques arrive with frequency rarely seen in other fields, making it essential for scientists that require mouse genetics for their work to keep up with the rapid progress of the technology to enable the best possible science. An area of mouse genetics that has been gaining traction over the last couple of years is the use of somatic genome engineering, targeting specific tissues and organs in vivo, or ex vivo, in explants or organ-like tissues cultures. These advances allow to address biological problems that require the complexity of the tissue context, without the slow and costly generation of mouse models de novo. This will be a main focus of this iteration of the practical course. This EMBO Practical Course will provide hands-on training in the latest techniques by leading experts in the field, complemented by a strong panel of speakers, including pioneers of CRISPR, mouse developmental biology, genetics and bioethics.

 

Speakers

 

Programme

 

Registration

  • Registration Deadline
  • 30 April 2019
  • Abstract Submission Deadline
  • 30 April 2019
  • Chosen Participants Will Be Notified By
  • 13 May 2019
  • Payment Deadline
  • 10 June 2019

 

  • STUDENT/POSTDOCS EUR 500
  • ACADEMIC EUR 500

Registration includes:

  • Participation in all lectures and practicals
  • Accommodation
  • All meals including closing barbecue
  • Social event
  • Trip to Prague

Payment

Selected participants will be notified on how to pay the registration fee.

Selection criteria

Applicants with ongoing or future projects that require direct genome engineering expertise as well as from institutions that are able to further disseminate the experience gathered in the course to the local research communities will be preferred.

Motivation Letter guidelines

Please write a brief and concise, one page motivation letter, describing:

a) your scientific background, and topics you are currently working on

b) previous genome engineering experience

c) how would your research plans benefit from the skills acquired in the course

d) the current state of the infrastructure for mouse experimentation at your host institution

Poster specifications

Each participant is asked to present a poster showing recent work.

Size Width x Height (mm) Width x Height (in)

A0 841 x 1189 mm 33.1 x 46.8 in

Travel grants

A limited number of travel grants are available for participants. Applicants do not need to apply separately for travel grants for this event but should indicate on the registration form if they wish to be considered for a travel grant. Selection of awardees is handled directly by the organizer who will notify all eligible participants. More information is available at EMBO Travel Grants' page.

Child care grant

EMBO Courses and Workshops offers grants to offset additional child care costs incurred by participants or speakers when participating at any EMBO Courses and Workshop funded meeting. Eligible costs include fees for a caregiver or child-care facility, travel costs for a caregiver, or travel costs for taking the child to the meeting etc. Please indicate on the registration form whether you would like to be considered for the grant. Please also describe how you intend to use the child care grant and specify the sum that you will need.

 

Contact

 

 

Venue

Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

The Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), founded in 1998, is one of 80 institutes of the Max Planck Society, an independent non-profit organization in Germany is part of the Dresden Campus. The Dresden Campus has a strong background in genome engineering. Recombineering, the basis of efficient genome engineering in mouse ES cells was developed in the lab of Francis Stewart (co-organizer). In addition we have three facilities that routinely generate mouse mutants and work closely together, namely the Genome Engineering Facility at MPI CBG, the Transgenic core facility MPI CBG and Carus Genomics Facility at Faculty of Medicine, each headed by one of the organizers.

Accommodation

The participants will be accommodated in the Hotel am Blauen Wunder

The hotel is within walking distance of the MPI-CBG.

For directions, see here.

One can also use the public transport to get closer to the Institute starting from Prellerstraße Dresden Augsburger Straße, TRAM num. 6, 12.

Two participants will share one room.

Transport

VIA PLANE

Dresden has a relatively small airport connected by Lufthansa to major German hubs such as Frankfurt, Munich and Duesseldorf. There is also an AirFrance flight from London City. http://www.dresden-airport.de/

Berlin Schoenefeld International airport is about 172 km from Dresden, easily reachable by regular trains.

Vaclav Havel Airport Prague in the Czech Republic is another option, 160 km away, also connected by trains about every two hours.

From the Dresden Airport, please take the train S2 (every 30 min) to the train station Bahnhof-Neustadt. Then take the tram no. 6, direction Niedersedlitz, to the station Königsheimplatz. Cross the street and walk along the street Schubertstrasse till you come to Pfotenhauerstrasse and turn left. Our institute is at Pfotenhauerstrasse 108. The building is green and blue. [approx. 40 mins.]

VIA TRAIN

Dresden is easily reachable by train. There are two train stations in Dresden: Hauptbahnhof and Bahnhof Neustadt

From the main train station [Hauptbahnhof] please take the tram no. 10, direction Striesen, to the station Fetscherplatz. Then take the tram no. 12, direction Striesen, to the station Königsheimplatz. Cross the street and walk along the street Schubertstrasse till you come to Pfotenhauerstrasse and turn left. Our institute is at Pfotenhauerstrasse 108. The building is green and blue. [approx. 20 mins.]

You can also use tram no. 3 (Wilder Mann) or 7 (Weixdorf) and change at Pirnaischer Platz to bus line 62 (Johannstadt). The terminal stop is right opposite ofthe Institute. [approx. 23 mins.]

From the train station Bahnhof Neustadt take tram no. 6, direction Niedersedlitz, to the station Königsheimplatz. Cross the street and walk along the street Schubertstrasse till you come to Pfotenhauerstrasse and turn left. Our institute is at Pfotenhauerstrasse 108. The building is green and blue. [approx. 15 mins.]

Reaching the Institute via tram or bus

Take tram no. 6 or no. 12 to the station Königsheimplatz. Walk along the street Schubertstrasse till you come to Pfotenhauerstrasse and turn left.

Alternatively, take bus no. 62 or no. 74 to Johannstadt. Our institute is at Pfotenhauerstrasse 108. The building is green and blue.

To check the schedule of public transport use this website.

VIA CAR

from Berlin (north)

Leave Autobahn A4 at the exit Dresden-Hellerau, which will take you onto the B 170 heading towards the city center (Zentrum). Stay on the B 170 for about 5 km until it reaches the intersection "Carolaplatz". At the next intersection turn right onto the "Albertbrücke" bridge. From now on follow the signs "Uniklinikum" to the medical clinic. Once over the bridge, you have to drive a circle in order to turn to the left, which means taking the second street to the right, then turn to the right and to the right again onto "Käthe-Kollwitz-Ufer". Follow "Käthe-Kollwitz-Ufer" and turn right into "Fetscherstrasse". At the first intersection turn left into "Pfotenhauerstrasse". Our institute is on the right at Pfotenhauerstrasse 108. The building is green and blue.

from Munich/Frankfurt/Leipzig (south)

Leave Autobahn A4 at the exit Dresden-Altstadt, which will take you onto the B 6. Follow the signs to the city center (Zentrum) and stay on the B 6 for about 4 km until an intersection with a Turkish Mosque on the left side. Still following the signs to the city center (Zentrum), turn left and pass the Mosque. Follow the road which turns to the right and goes under the railway bridge. This leads you to "Uferstrasse" which takes two sharp bends (passing Semperoper opera house). Now you are on the "Terrassenufer" which takes you parallel to the river Elbe. Stay on this road following the sign "Uniklinikum". The street merges to "Käthe-Kollwitz-Ufer". Follow "Käthe-Kollwitz-Ufer" and turn right into "Fetscherstrasse". At the first intersection turn left into "Pfotenhauerstrasse". Our institute is on the right at Pfotenhauerstrasse 108. The building is green and blue.

from Prague

Follow the highway D8 going north from the Prague circle towards Aussig (Usti nad Labem) or Teplitz (Teplice) and Dresden. The highway is interrupted in the middle by the scenic Ceske Stredohori mountain for about 20 km (narrow road, follow signs for Dresden). The trip takes about 2 hours.

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