About the Practical Course
In collaboration with EMBO, we are looking forward to host yet another practical course in Odense, Denmark. Attending this EMBO Practical Course will provide you with hands-on experience within the field of protein post-translational modifications (PTMs) and you will obtain a new and solid network of scientists having interests similar to yours. Our bright new laboratory and large mass spectrometry instrument park will provide the physical framework for the 8-day course.
Modifications of proteins isan essential mechanism used by cells to achieve a tight and controlled regulation of cellular mechanisms and perturbations in PTM regulation often leads to serious diseases. Increasing evidence suggest that PTMs are frequently not working alone but can have significant influence on the presence and function of other PTMs in a way that a given PTM of a given protein can affect other PTMs either on the same or other proteins, leading to distinct functional patterns of PTMs on proteins, tightly regulating important functions in the cell, a phenomenon termed PTM cross-talking.
This EMBO Practical Course aims to provide a theoretical and practical overview of state-of-art techniques for the characterization of various PTMs, such as phosphorylation, acetylation, cysteine PTMs and glycosylation, and their cross-talking in controlling dynamic cellular mechanisms.
The laboratory part will focus on a case study of EGF stimulated SILAC labeled HeLa cells. You will be introduced to enrichment, identification and quantitation of the PTM peptides and to mass spectrometry analysis as well as data interpretation and bioinformatics. This will provide you with knowledge needed to perform quantitative large scale PTMomics from small amount of sample material yourself. You will be taught in methods developed in the laboratories of the speakers and they will provide you with their own tips and tricks.
In addition to lectures and laboratory work the program contains poster sessions, group discussions, learning activities, and social events. All students will be accommodated together in a nice hotel in the center of the birth city of H.C. Andersen.
Below you find some comments from participants from the last years:
"The overall organization of the course was excellent."
"I would like to highlight speakers expertis and willingness to share knowledge with everyone."
"There were also 10 minutes oral presentations of each participant, which was a great opportunity to exchange ideas."
"The laboratory facilities are exceptionally good for a practical course about mass spectrometry."
"I was feeling very well all the time, which surely contributed to my steep learning curve."