About the Workshop
Mitochondria are cells’ energy centers and a central point where a number of signaling pathways leading to cell death converge, leading to activation of apoptotic machinery and impairment of cells’ bioenergetic functions. Moreover, cellular homeostasis is regulated through mitophagy, the specific elimination of mitochondria through autophagy. Since both cellular metabolism and apoptotic pathways are compromised in many cancers, mitochondria-targeting drugs are considered as viable alternatives to eradicate chemotherapy-resistant cancer cells, since they directly initiate mitochondrial perturbations independently of upstream signaling events. This will provide novel insights into the control of mitochondrial functions and their deregulation in human cancers that has a major potential for development of innovative cancer therapeutics.
The overall aim of this EMBO Workshop is to bring together world leaders in several areas of biology and medicine, focusing on mitochondria and cancer from the point of view of cell death, the most efficient way to combat cancer.
About EMBO Courses and Workshops
EMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender).
Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.
